| Comments |
The NFS-70 C-10 cell line was derived from a lymphoma arising in a mouse inoculated with CAS-NS-7 ecotropic murine leukemia virus. The cells bear markers of pro-B lymphoblasts (Mac 1, CD11b. Ly 17, CD32. Ly 1, CD5. Lyb 2, Ly 5(B220), CD45R). They are negative for ThB, surface immunoglobulin (sIg) and Ia. The cells appear to be at a very early stage of commitment to B cell differentiation. Tested and found negative for ectromelia virus (mousepox). |
| References |
Davidson WF, et al. A unique series of lymphomas related to the Ly-1+ lineage of B lymphocyte differentiation. J. Immunol. 133: 744-753, 1984. PubMed: 6330201
Hay, R. J., Caputo, J. L., and Macy, M. L., Eds. (1992), ATCC Quality Control Methods for Cell Lines. 2nd edition, Published by ATCC.
Caputo, J. L., Biosafety procedures in cell culture. J. Tissue Culture Methods 11:223-227, 1988.
Fleming, D.O., Richardson, J. H., Tulis, J.J. and Vesley, D., (1995) Laboratory Safety: Principles and Practice. Second edition, ASM press, Washington, DC.
Biosafety in Microbiological and Biomedical Laboratories, 5th ed. HHS. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. Washington DC: U.S. Government Printing Office; 2007. The entire text is available online.
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