This material is contaminated with fungal and bacterial organisms. Virions of the papilloma viruses of man, cattle, dog and rabbit, show no antigenic similarities by agar gel immunodiffusion. Precipitin antibodies have been demonstrated. One to two drops of the cutaneous papilloma suspension, when rubbed into a scarified area of skin, will elicit tumor formation on the skin of susceptible calves within 30-60 days. |
