| 產(chǎn)品名稱 | Candida parapolymorpha Suh et Zhou |
|---|---|
| 商品貨號 | B170438 |
| Deposited As | Hansenula polymorpha de Morais et Maia, teleomorph |
| Strain Designations | DL-1 [NRRL Y-7560] |
| Application | produces 2-butanone alcohol dehydrogenase produces formaldehyde produces hydrogen peroxide produces isopropanol dehydrogenase (NADP) secondary alcohol dehydrogenase produces methyl ketones transformation host utilizes methanol reduces 4-chloro-1-(4-fluorophenyl)butan-1-one transformation host for expression of hirudin gene |
| Biosafety Level | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format | frozen |
| Storage Conditions | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain | yes |
| Disclosure | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol® | no |
| Genome Sequenced Strain | Yes |
| Comments | Mitochondrial genome sequenced strain. Ref
  Eldarov MA, et al. Complete sequence and analysis of the mitochondrial genome of the methylotrophic yeast Hansenula
polymorpha DL-1. FEMS Yeast Res. 11(6):464-472, 2011. PubMed: 21545683.Genome sequencing strain (the Joint Genome Institute at the Department of Energy, USA; Korea Research Institute of Bioscience and Biotechnology, S. Korea; Centre 'Bioengineering' RAS, Russia). |
| Medium | ATCC® Medium 28: Emmons' modification of Sabouraud's agar ATCC® Medium 200: YM agar or YM broth ATCC® Medium 1245: YEPD |
| Growth Conditions | Temperature: 24°C to 26°C
Atmosphere: Typical aerobic |
| Sequenced Data |
SSU rDNA of ATCC 26012
AAAGATTAAGCCATGCATGTCTAAGTATAAGCAATTTATACAGTGAAACTGCGAATGGCTCATTAAATCAGTTATCGTTTATTTGATAGTTCCTTTACTACATGGATAACCGTGGTAATTCTAGAGCTAATACATGCTTAAAGCCCCGACTTCTGGAAGGGGTGTATTTATTAGATAAAAAATCAATGCCTTCGGGCTTTTTGATGATTCATAATAACTTTTCGAAGCTCATGGCCTTGTGCTGGAGCTGGTTCATTCAAATTTCTGCCCTATCAACTTTCGATGGTAGGATAGTGGCCTACCATGGTTTTCACGGGTAACGGGGAATAAGGGTTCGATTCCGGAGAGGGAGCCTGAGAAACGGCTACCACATCCAAGGAAGGCAGCAGGCGCGCAAATTACCCAATCCTGACACAGGGAGGTAGTGACAATATATAACGATACAGGGCCCTTTCGGGTCTTGTAATTGGAATGAGTACAATGTAAATACCTTAACGAGGAACAATTGGAGGGCAAGTCTGGTGCCAGCAGCCGCGGTAATTCCAGCTCCAATAGCGTATATTAAAGTTGTTGCAGTTAAAAAGCTCGTAGTTGAACCTTGGGTCTGGTTAGCCGGTCTGCCTTTTTTGGCACGTACTGGATTTAACCGGGCCTTTCCTTCTGGCTAACCAACACTCTGTGTTGGCAAACCAGGACTTTTACTTTGAAAAAATTAGAGTGTTCAAAGCAGGCCTTTGCTCGAATATATTAGCATGGAATAATAGAATAGGACGTTATGGTTCTATTTTGTTGGTTTCTAGGACCATCGTAATGATTAATAGGGACGGTCGGGGGCATCAGTATTCAGTTGTCAGAGGTGAAATTCTTGGATTTACTGAAGACTAACTACTGCGAAAGCATTTGCCAAGGACGTTTTCATTAATCAAGAACGAAAGTTAGGGGATCGAAGATGATCAGATACCGTCGTAGTCTTAACCATAAACTATGCCGACTAGGGATCGGGTGGTGTTTCTTTTTTGACCCACTCGGCACCTTACGAGAAATCAAAGTTTTTGGGTTCTGGGGGGAGTATGGTCGCAAGGCTGAAACTTAAAGGAATTGACGGAAGGGCACCACCAGGAGTGGAGCCTGCGGCTTAATTTGACTCAACACGGGGAAACTCACCAGGTCCAGACACAATAAGGATTGACAGATTGAGAGCTCTTTCTTGATTTTGTGGGTGGTGGTGCATGGCCGTTCTTAGTTGGTGGAGTGATTTGTCTGCTTAATTGCGATAACGAACGAGACCTTAACCTACTAAATAGTGATATTGGCTTTTGCTGATTTTCACTTCTTAGAGGGACTATCGGTTTCAAGCCGATGGAAGTTTGAGGCAATAACAGGTCTGTGATGCCCTTAGACGTTCTGGGCCGCACGCGCGCTACACTGACGGAGCCAACGAGCTCTATCCTTGACCGAGAGGTCCGGGTAATCTTGTGAAACTCCGTCGTGCTGGGGATAGAGCATTGCAATTATTGCTCTTCAACGAGGAATTCCTAGTAAGCGCAAGTCATCAGCTTGCGTTGATTACGTCCCTGCCCTTTGTACACACCGCCCGTCGCTAGTACCGATTGAATGGCTTAGTGAGGCTTCAGGATTGGTTCAGAGAAGGGGGCAACTCCATCTTGGAACCGAGAATCTAGTCAAACTTGGTCATTTAGAGGAACTAAAA ITS of ATCC 26012 TTTCCGTAGGTGAACCTGCGGAAGGATCATTACAGTATTCTTCTAAGCTGGAGCTGTTAATTGATTGAACTGTTTGCCTGCGCTGCTGAAATACTGCGTGCGCGGTGATGGTTTTTTTGGTTGCAGTTCTACTCAAGGCTTAGAAATCTCCTTACACACTTTGTTTTCTTATTAGAGACAAATTTGCTTTGGCTAGCGGTCGTTTAAACGCGGCATGCCTGGCCAGAGGTTTTAACAAAACTCATTTTCGTCTTGCCCTCGTGGGAAGATTGAAAACTTGTATTATTATTTCGTCAGTTATAAGAAGTTGCGTTTGCAGCTTTTCTAAACTTTAAAACTTTCAACAACGGATCTCTTGGTTCTCGCATCGATGAAGAACGCAGCGAAATGCGATACGTAATGTGAATTGCAGATTTTCGTGAATCATTGAATCTTTGAACGCACATTGCGCCCTCTGGTATTCCAGAGGGCATGCCTGTTTGAGCGTCATTTCCCTCTCAAACCCCCGGGTTTGGTGATGGGCAATACTCTCGTCTGAGAGTTTGCTTGAAATGAATTGGCATGAGTTTTTGATACGAACTTCAGCTGTTTATTCAATGTATTAGGTTTTATCCATCGTTGATTGACAACTGCAAGCTTCTTTCAAAATTTGGCTCTGCCTTACAAACTTTAATCATAAAGTTTGACCTCAAATCAGGTAGGATTACCCGCTGAACTTAAGCATATCAAT D1/D2 region of LSU rDNA of ATCC 26012 ATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTGCCTTAGTAGCGGCGAGTGAAGCGGCAAGAGCTCAAATTTGAAATCTGGTACCTTCGGTGCCCGAGTTGTAATTTGAAGAAAGTAATCTTGGAGGTGGCCTTTGTCTATGTTCCTTGGAACAGGACGTCATGGAGGGTGAGAATCCCGTGTGATGAGGTGTCCATCTCCGTGTAAGATGCTTTCGAAGAGTCGAGTTGTTTGGGAATGCAGCTCAAAGTGGGTGGTAAATTCCATCTAAAGCTAAATATTGGCGAGAGACCGATAGCGAACAAGTACTGTGAAGGAAAGATGAAAAGAACTTTGAAAAGAGAGTGAAAAAGTACGTGAAATTGTTGAAAGGGAAGGGTATTTGATCAGACTTGGTATTTAGCTATCATCGCTCCTTGTGGGTGGTGCTCTAGCTTTTTACTGGGCCAGCATCAGTTTTGGTGGCAAGATAATGACAGTTGAATGTGGCTCCTCGGAGTGTTATAGCTTCTGTTGATATTGCCTACCGGGACTGAGGTCTGCGGCTTTTGCCTAGGATGCTGGCGTAATGATCCAATACCGCCCGT |
| Name of Depositor | DW Levine |
| U.S. Patent Number | |
| Chain of Custody | ATCC <-- DW Levine <-- CL Cooney |
| Isolation | Soil, Massachusetts |
| Cross References | Nucleotide (GenBank) : JN863704 RPB 2 gene Nucleotide (GenBank) : JN863698 RPB 1 gene Nucleotide (GenBank) : FJ914939 D1/D2 region of 28S rRNA gene Nucleotide (GenBank) : FJ914922 ITS including 5.8S rRNA gene Nucleotide (GenBank) : FJ914907 18S rRNA gene |
| References | Patel RN, et al. Method for producing microbial cells and use thereof to produce oxidation products. US Patent 4,266,034 dated May 5 1981 Patel RN, et al. Microbial reduction of 1-(4-fluorophenyl)-4-[4-(5-fluoro-2-pyrimidinyl)-1-piperazinyl]butan-1-one. Biotechnol. Appl. Biochem. 17: 139-153, 1993. PubMed: 8166884 Baratti J, et al. Preparation and properties of immobilized methanol oxidase. Biotechnol. Bioeng. 20: 333-348, 1978. Kim CH, et al. Effect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha. Biotechnol. Lett. 18: 417-422, 1996. Cooney CL, Levine DW. Microbial utilization of methanol. Adv. Appl. Microbiol. 15: 337-365, 1972. PubMed: 4593294 Kang HA, et al. Cloning and characterization of the Hansenula polymorpha homologue of the Saccharomyces cerevisiae PMR1 gene. Yeast 14: 1233-1240, 1998. PubMed: 9791894 Kushnirov VV. Rapid and reliable protein extraction from yeast. Yeast 16: 857-860, 2000. PubMed: 10861908 Bravo M, Wang DI. Enzymatic oxidation of methanol to produce formaldehyde and hydrogen peroxide. Adv. Biotechnol. 3: 329-334, 1981. Patel RN, et al. Oxidation of secondary alcohols to methyl ketones by yeasts. Appl. Environ. Microbiol. 38: 219-223, 1979. PubMed: 42348 Patel RN, et al. Microbial production of methyl ketones. Purification and properties of a secondary alcohol dehydrogenase from yeast. Eur. J. Biochem. 101: 401-406, 1979. PubMed: 230031 Suh SO, Zhou JJ. Methylotrophic yeasts near Ogataea (Hansenula) polymorpha: a proposal of Ogataea angusta comb. nov. and Candida parapolymorpha sp.nov. FEMS Yeast Res. 10: 631-638, 2010. PubMed: 20491937 Eldarov MA, et al. Complete sequence and analysis of the mitochondrial genome of the methylotrophic yeast Hansenula polymorpha DL-1. FEMS Yeast Res. 11(6):464-472, 2011. PubMed: 21545683. Ravin NV, et al. Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1. BMC Genomics 14: 837, 2013. PubMed: 24279325 |
| 梅經(jīng)理 | 17280875617 | 1438578920 |
| 胡經(jīng)理 | 13345964880 | 2438244627 |
| 周經(jīng)理 | 17757487661 | 1296385441 |
| 于經(jīng)理 | 18067160830 | 2088210172 |
| 沈經(jīng)理 | 19548299266 | 2662369050 |
| 李經(jīng)理 | 13626845108 | 972239479 |
