Degrades acridine to acridine trans-l,2-dihydrodiol and 2-hydroxyacridine
Detoxification of 1-nitropyrene
Oxidizes dibenzothiophene to dibenzothiophene sulphoxide and dibenzothiophene sulphone
Transformation of benz[a]anthracene to trans-dihydrodiols
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
frozen
Storage Conditions
Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
After 10 days colonies spreading rapidly, at first white, later with dark spots of conidia, becoming gray, conidiophores erect, with verticillate or solitary branches; vesicles subglobose to pyriform, verrucose or smooth, conidia globose. 7-11 μm, or ovoid to ellipsoidal, 6-10 x 9-13 μm, smooth, verruculose, or shortly echinulate, hyaline, or with granular contents, brownish in mass.
Medium
ATCC® Medium 200: YM agar or YM broth
ATCC® Medium 323: Malt agar medium
ATCC® Medium 336: Potato dextrose agar (PDA)
Nucleotide (GenBank) :
Y17297
Cunninghamella elegans mRNA for 6-phosphogluconate dehydrogenase.
References
Perry JJ, Cerniglia CE. Effect of substrate on the fatty acid composition of hydrocarbon-utilizing filamentous fungi. J. Bacteriol. 118: 844-847, 1974. PubMed: 4829928
Cerniglia CE, et al. Fungal metabolism and detoxification of the nitropolycyclic aromatic hydrocarbon 1-nitropyrene. Appl. Environ. Microbiol. 50: 649-655, 1985. PubMed: 3907498
Crawford DL, Gupta RK. Oxidation of dibenzothiophene by Cunninghamella elegans. Curr. Microbiol. 21: 229-231, 1990.
Cerniglia CE, et al. Effects of a fluoro substituent on the fungal metabolism of 1- fluoronaphthalene. Appl. Environ. Microbiol. 48: 294-300, 1984. PubMed: 6486779
Cerniglia CE, et al. Stereoselective fungal metabolism of methylated anthracenes. Appl. Environ. Microbiol. 56: 661-668, 1990. PubMed: 2317041
Pothuluri JV, et al. Fungal metabolism and detoxification of fluoranthene. Appl. Environ. Microbiol. 58: 937-941, 1992. PubMed: 1575497
Pothuluri JV, et al. Fungal metabolism of acenaphthene by Cunninghamella elegans. Appl. Environ. Microbiol. 58: 3654-3659, 1992. PubMed: 1482186
Pothuluri JV, et al. Biotransformation of fluorene by the fungus Cunninghamella elegans. Appl. Environ. Microbiol. 59: 1977-1980, 1993. PubMed: 8328814
Sutherland JB, et al. Enantiomeric composition of the trans-dihydrodiols produced from phenanthrene by fungi. Appl. Environ. Microbiol. 59: 2145-2149, 1993.
Cerniglia CE, et al. Metabolism of benz[a]anthracene by the filamentous fungus Cunninghamella elegans. Appl. Environ. Microbiol. 60: 3931-3938, 1994. PubMed: 7993083
Wong YW, Davis PJ. Microbial models of mammalian metabolism: production of 3'- hydroxywarfarin, a new metabolite of warfarin using Cunninghamella elegans. J. Pharm. Sci. 80: 305-308, 1991. PubMed: 1865328
Schlenk D, et al. P450 catalysed S-oxidation of dibenzothiophene by Cunninghamella elegans. Xenobiotica 24: 1077-1083, 1994. PubMed: 7701849
Hansen EB Jr., et al. Fungal transformations of antihistamines: metabolism of brompheniramine, chlorpheniramine, and pheniramine to N-oxide and N- demethylated metabolites by the fungus Cunninghamella elegans. Xenobiotica 25: 1081-1092, 1995. PubMed: 8578764
Pothuluri JV, et al. Biotransformation of 1-nitrobenzo[e]pyrene by the fungus Cunninghamella elegans. J. Ind. Microbiol. Biotechnol. 22: 52-57, 1999.
Wang RF, et al. Cloning, sequencing, and expression of the gene encoding enolase from Cunninghamella elegans. Mycol. Res. 104: 175-179, 2000.
Cerniglia CE, Perry JJ. Crude oil degradation by microorganisms isolated from the marine environment. Z. Allg. Mikrobiol. 13: 299-306, 1973. PubMed: 4797813
Sutherland JB, et al. Identification of metabolites produced from acridine by Cunninghamella elegans. Mycologia 86: 117-120, 1994.
Sutherland JB, et al. N-Oxidation of quinoline and isoquinoline by Cunninghamella elegans. Exp. Mycol. 18: 271-274, 1994.
Kim YH, et al. Decolorization of malachite green by cytochrome c in the mitochondria of the fungus Cunninghamella elegans. Arch Biochem Biophys 494: 159-165, 2010. PubMed: 19944668
