p 28 protein cross-reacts with Visna p 28 in gel diffusion.
Biosafety Level
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Isolation
Synovial membrane cell explants from a 5-year-old male goat with chronic arthritis
Product Format
freeze-dried
Storage Conditions
-60°C or colder
Comments
p 28 protein cross-reacts with Visna p 28 in gel diffusion.
Positive for bacterial growth on blood agar. Bacteria sensitive to penicillin, ampillicin, neomycin and vancomycin
Effect on Host
Multinucleation of cells with eventual cell death
Recommended Host
neonatal goat synovial membrane cells
caprine synovial cells
Growth Conditions
Temperature: 37°C
Incubation: 4-8 days
Name of Depositor
P Anderson, DS Adams, P Klevjer
Source
Synovial membrane cell explants from a 5-year-old male goat with chronic arthritis
References
Crawford TB, et al. Chronic arthritis in goats caused by a retrovirus. Science 207: 997-999, 1980. PubMed: 6153243
Adams DS, et al. A pathogenetic study of the early connective tissue lesions of viral caprine arthritis-encephalitis. Am. J. Pathol. 99: 257-278, 1980. PubMed: 6990770
Cross References
Nucleotide (GenBank) :
L78445
Caprine arthritis-encephalitis virus (strain 75-G63) pol protein gene, partial cds.
