| 產品名稱 |
Geomyces destructans Blehert et Gargas |
| 商品貨號 |
B240060 |
| Strain Designations |
20631-21 |
| Synonym |
Pseudogymnoascus destructans |
| Application |
Emerging infectious disease research |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format |
frozen |
| Storage Conditions |
Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section |
| Type Strain |
yes |
| Preceptrol® |
no |
| Genome Sequenced Strain |
Yes
|
| Comments |
Psychrophilic fungus.
Pathogen causing bat white-nose syndrome.
Genome sequencing strain (The Broad Institute, USA).
Individuals that have contact with G. destructans should observe a personal quarantine and not enter bat congregation sites during active work and for 7 days after last contact with the fungus. Lab processes should be managed to avoid inadvertent contact with culture materials. Clothing and other materials brought into the laboratory should be segregated from those transported to any potential bat congregation sites.
The current accepted name of Geomyces destructans is Pseudogymnoascus destructans (Blehert et Gargas) Minnis et Lindner. |
| Morphology |
On SDA at 10°C after 38 days, colonies white to grayish white, raised, dense velvety texture, slow growing, colony diameter after 38 days 1.8-2.3 cm. Production of light to dark brown exudate. Reverse buff to tan. Hyphae guttulate, 2.25 μm thick. Conidiophores with whorls of 2-6 verticils. Conidia formed singly and in short chains of 2-5, smooth, amygdaliform to allantoids with apical scar, containing oil droplets, 6-10.5 μm x 3-4.5 μm. |
| Medium |
ATCC® Medium 336: Potato dextrose agar (PDA)
ATCC® Medium 28: Emmons' modification of Sabouraud's agar
|
| Growth Conditions |
Temperature: 4°C to 10°C Atmosphere: Typical aerobic |
| Sequenced Data |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence
AAGTATGGAGCAATCTCAATGATTCTTCCGTGGCGACACTTATGGAAGCCTTTGCAGCCCCGCAAGGGGTGGGGAGCACGACTGTAAATAAGTCTCCCTTCATGCAAGTCAGCACCCGCTGGCAACACGATCGAATTGACGGGGACGTCCTAAAGCCTACAACACCAACCCGCCCGGGAAACCGAGGCGGGGGCCCGTGCTAACTCCACGGGGTGGTAAAAGAGTGTATGGATACTCCCTCTGGGGAACTATGGATAATCCGCAGCGAAGACCCTAAGTAGCGCTAGCTATACGGGTAACGTTCACAGACTAAGTGGTTGTGGGTGGAGCCTAGCTCTGCTTAAGATATAGTCGGGCCCTACGTGAAAGCGCAGGGGTGAGTCGCTACGAACTCGAAACCGTTCCGTAGGTGAACCTGCGGAAGGATCATTACAGTAGTCGCCCGGGTTGCCGCAAGGCCTCCCGGGTAACCTACCACCCTTTGTTTATTACACTTTGTTGCTTTGGCAGGCCTGCCCTCGGGCTGCTGGCTCCGGCCGGCGAGCGCTTGCCAGAGGACTAAACTCTGTTTGTCTATACTGTCTGAGTACTATATAATAGTTAAAACTTTCAACAACGGATCTCTTGGTTCTGGCATCGATGAAGAACGCAGCGAAATGCGATAAGTAATGTGAATTGCAGAATTCAGTGAATCATCGAATCTTTGAACGCACATTGCGCCCCCTGGTATTCCGGGGGGCATGCCTGTCCGAGCGTCATTACAACCCTCAAGCTCAGCTTGGTATTGGGCCCCGCCGACCCGGCGGGCCCTAAAGTCAGTGGCGGTGCCGTCCGGCTCCGAGCGTAGTAATTCTTCTCGCTCCGGAGGTCCGGTCGTGTGCTTGCCAGCAACCCCCAATTTTTTCAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAGCATATCAATAA
D1D2 region of the 28S ribosomal RNA gene
ATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTACCTCAGTAACGGCGAGTGAAGCGGTAACAGCTCAAATTTGAAATCTGGCCTCACGGTCCGAGTTGTAATTTGTAGAGGATGCTTCGAGCATGGTCTGGCCTAAGTTCCTTGGAACAGGACGTCATAGAGGGTGAGAATCCCGTATGCGGCCAGGTGCCTACGCTCATGTGAAGCTCCTTCGACGAGTCGAGTTGTTTGGGAATGCAGCTCAAAATGGGTGGTAAATTTCATCTAAAGCTAAATATTGGCCAGAGACCGATAGCGCACAAGTAGAGTGATCGAAAGATGAAAAGCACTTTGGAAAGAGAGTTAAACAGTACGTGAAATTGTTGAAAGGGAAGCGCTTGCAACCAGACTTGCGCGCGGCCGATCATCCGGTGTTCTCACCGGTGCACTCGGCCGTGCTCAGGCCAGCATCGGTTTTGGCGGCTGGATAAAGGCCCTAGGAATGTAGCTCCTCTCGGGGAGTGTTATAGTCTAGGGTGCAATGCAGCCTGCTGGGACCGAGGACCGCGCTTCGGCTAGGATGCTGGCGTAATGGTTGTAAGCGGC
|
| Name of Depositor |
DS Blehert |
| Special Collection |
ATCC |
| Chain of Custody |
ATCC <-- DS Blehert |
| Isolation |
Wing skin of Myotis lucifugus, little brown bat, in Williams Hotel Mine, Ulster County, New York, USA, February 2008. |
| Cross References |
Nucleotide (GenBank) :
KC171349
ITS including 5.8S rRNA gene
Nucleotide (GenBank) :
KC171321
D1/D2 region of 28S rRNA gene
Nucleotide (GenBank) :
EU884921
Geomyces destructans isolate 20631-21 small subunit ribosomal RNA gene, partial sequence; internal transcribed spacer 1 and 5.8S ribosomal RNA gene, complete sequence; and internal transcribed spacer 2, partial sequence.
Nucleotide (GenBank) :
FJ231098
Geomyces destructans isolate 20631-21 18S small subunit ribosomal RNA gene, partial sequence.
Nucleotide (GenBank) :
AEFC00000000
Pseudogymnoascus destructans 20631-21, whole genome shotgun sequencing project
Nucleotide (GenBank) :
LAJJ00000000
Pseudogymnoascus destructans strain 20631-21, whole genome shotgun sequencing project
|
| References |
Gargas A, et al. Geomyces destructans sp. nov. associated with bat white-nose syndrome. Mycotaxon 108: 147-154, 2009.
Lorch JM, et al. Experimental infection of bats with Geomyces destructans causes white-nose syndrome. Nature 480: 376-378, 2011. PubMed: 22031324
Blehert DS, et al. Bat white-nose syndrome: an
emerging fungal pathogen? Science 323(5911): 227, 2009. PubMed: 18974316
Chaturvedi V, et al. Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with White Nose Syndrome (WNS). PLoS One 5(5): e10783, 2010. PubMed: 20520731
|
