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<em>Penicillium meloforme</em> Udagawa et Horie

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產品名稱	Penicillium meloforme Udagawa et Horie
商品貨號	B241332
Deposited As	Eupenicillium brefeldianum (Dodge) Stolk et Scott
Strain Designations	C39686
Application	produces 1H-cycloundeca[1,2-B:5,6-B'] biscyclohepta(B)pyrans produces eupenifeldin
Biosafety Level	1 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format	frozen
Storage Conditions	Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Type Strain	no
Disclosure	This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Preceptrol®	no
Medium	ATCC^® Medium 325: Malt extract agar (Blakeslee's formula) ATCC^® Medium 336: Potato dextrose agar (PDA)
Growth Conditions	Temperature: 24°C to 26°C Atmosphere: Typical aerobic
Sequenced Data	18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence AAGGATCATTACCGAGTGAGGGCCCTCTGGGTCCAACCTCCCACCCGTGTTTATCGTACCTTGTTGCTTCGGCGGGCCCGCCGTCATGGCCGCCGGGGGGCACCCGCCCCCGGGCCCGTGCCCGCCGAAGACACCCCTGAACGCTGTCTGAAGATTGCAGTCTGAGCGATTAGCTAAATCAGTTAAAACTTTCAACAACGGATCTCTTGGTTCCGGCATCGATGAAGAACGCAGCGAAATGCGATAAGTAATGTGAATTGCAGAATTCAGTGAATCATCGAGTCTTTGAACGCACATTGCGCCCCCTGGTATTCCGGGGGGCATGCCTGTCCGAGCGTCATTGCTGCCCTCAAGCACGGCTTGTGTGTTGGGCCCCCGCCCCCCGGTCCCGGGGGGCGGGCCCGAAAGGCAGCGGCGGCACCGCGTCCGGTCCTCGAGCGTATGGGGCTTCGTCACCCGCTCTGTAGGCCCGGCCGGCGCCCGCCGGCGACCCCCATCAATCTTTCCAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAG D1D2 region of the 28S ribosomal RNA gene CATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTGCCTCAGTAACGGCGAGTGAAGCGGCAAGAGCTCAAATTTGAAAGCTGGCTCCTTCGGGGTCCGCATTGTAATTTGCAGAGGATGCTTCGGGAGCGGCCCCCATCTAAGTGCCCTGGAACGGGCCGTCATAGAGGGTGAGAATCCCGTCTGGGATGGGGTGCCCGCGCCCGTGTGAAGCTCCTTCGACGAGTCGAGTTGTTTGGGAATGCAGCTCTAAATGGGTGGTAAATTTCATCTAAAGCTAAATACTGGCCGGAGACCGATAGCGCACAAGTAGAGTGATCGAAAGATGAAAAGCACTTTGAAAAGAGAGTTAAACAGCACGTGAAATTGTTGAAAGGGAAGCGCTTGCGACCAGACTCGCCCGCAGGGTTCAGCCGGCACTCGTGCCGGTGTACTTCCCCGCGGGCGGGCCAGCGTCGGTTTGGGCGGCCGGTCAAAGGCCCTCGGAATGTAACGCCCCCCGGGGCGTCTTATAGCCGAGGGTGCCATGCGGCCAGCCCGGACCGAGGAACGCGCTTCGGCTCGGACGCTGGCATAATGGTCGTAAGCGA Beta-tubulin (BenA) partial gene TGGTACGTGCCACGCCCGCCAAAAAACATCCCCAGCACAACAAAGCAACCCCCCAATTGCGAGTCTCAATGGGCAGAACATACTGACTCGAACTACAGGCAGACCATTGCTGGTGAGCACGGCCTTGACGGCGATGGCCAGTAAGTTTCTTCGATACCACTCGATACCACTCGACGCGGAATGGCGGTCTGATGTTTTTGGCTAGCTACAATGGTACCTCCGACCTCCAGCTGGAGCGCTTGAACGTCTACTTCACCCACGTAAGTTGCGTGTCCATTTAACGCAGAAACGCCGGAATCGACTCTAACCCATGGATGTTTTGTTTTTTAGGCCAGCGGTGACAAGTACGTTCCCCGTGCCGTTCTGGTCGATCTGGAGCCTGGTACCATGGATGCTGTCCGTGCCGGTCCCTTTGGCAAGCTCTTCCGTCCCGACAACTTCGTCTTCGGCCAGTCCGGTGCCGGTAACAACTGGGCCAAGGGT
Name of Depositor	Bristol-Myers Squibb Co.
U.S. Patent Number	5,284,866
Special Collection	NCRR Contract
Isolation	Soil, Shimane, Japan
References	Mayerl F, et al. 1H-cycloundeca[1,2-B:5,6-B']biscyclohepta(B)pyrans usefuel as antitumor agents. US Patent 5,284,866 dated Feb 8 1994 Mayerl F, et al. Eupenifeldin, a novel cytotoxic bistropolone from Eupenicillium brefeldianum. J. Antibiot. 46: 1082-1088, 1993. PubMed: 8360103

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